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Not evaluated by SAHPRA · For information & research use only · Not intended to diagnose, treat, cure or prevent any disease · Consult a healthcare professional
This product has not been evaluated by SAHPRA. For information purposes only — not intended to diagnose, treat, cure or prevent any disease.
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PerformanceResearch vialNNMT inhibitorsmall moleculeNAD+adiposeresearch

Amino-1MQ

NNMT inhibitor for adipose and NAD+ research

R 845
10mg vial
Suppresses lipogenesisIn 3T3-L1 adipocytes, dose-dependently suppressed lipogenesis (50% at 30 µM, 70% at 60 µM).
Adipose-tissue effects in mice11 days of dosing in diet-induced obese mice produced ~5% body-weight loss and ~35% reduction in epididymal white adipose mass.
Raises intracellular NAD+ and SAMBlocking NNMT spares NAD+ precursors and methyl donors that the enzyme normally consumes.
Independent of food intakeMouse weight loss occurred without changes in food intake — a metabolic, not appetite, mechanism.
"Amino" in research-peptide catalogues at this price point and dose is the small-molecule **5-amino-1-methylquinolinium (5-Amino-1MQ)** — a selective inhibitor of nicotinamide N-methyltransferase (NNMT). It is not a peptide; it is a quinolinium scaffold sold alongside peptides because it is used in the same body-composition research context. NNMT methylates nicotinamide into 1-methylnicotinamide, consuming both NAD+ precursors and methyl donors. Inhibiting it raises intracellular NAD+ and SAM, and in adipocytes it suppresses lipogenesis.
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Elegant Slimming · Mokopane, Limpopo, South Africa
WhatsApp 076 547 8764 · Mon–Sat 9–5
Regulatory
This product has not been evaluated by the South African Health Products Regulatory Authority (SAHPRA).
For information purposes only — not intended to diagnose, treat, cure or prevent any disease.