Skip to content
Not evaluated by SAHPRA · Research & educational information only · Nothing on this site is for sale · Not medical advice · Consult a healthcare professional
Not evaluated by SAHPRA. Research & educational information only — nothing is for sale; not intended to diagnose, treat, cure or prevent any disease.
← Back to catalogue
IGF-1 LR3
PerformanceResearch vialIGF-1 analoghypertrophylong-actinganabolicrecovery

IGF-1 LR3

Long-acting IGF-1 analog for hypertrophy research

Format
Research vial
Strength / pack
1mg vial
Category
Performance
Extended half-life~20–30 hours versus minutes for native IGF-1 — a single daily injection sustains exposure.
Higher free fraction100× lower IGFBP affinity means more bioavailable peptide at lower doses.
Hypertrophy pathwayActivates PI3K / Akt / mTOR for protein synthesis and anti-atrophy signalling via FoxO suppression.
Satellite cell and proliferation effectsMAPK / ERK signalling drives myoblast proliferation in cell-culture and animal models.
IGF-1 LR3 (Long R3 IGF-1) is an 83-amino-acid synthetic analog of insulin-like growth factor 1 with a 13-residue N-terminal extension and an arginine substituted for glutamic acid at position 3. The Arg-3 substitution drops affinity for IGF binding proteins (IGFBPs) ~100-fold while preserving full agonism at the IGF-1 receptor, so more of the injected peptide is free to bind tissue. Half-life is ~20–30 hours versus minutes for native IGF-1. Downstream signalling runs through PI3K/Akt/mTOR (protein synthesis, anti-atrophy) and MAPK/ERK (proliferation).
More in Performance

Related research

PerformanceResearch vial
CJC-1295 + Ipamorelin
10mg vial

CJC-1295 + Ipamorelin

A two-peptide blend pairing the GHRH analog CJC-1295 (without DAC / Modified GRF 1-29) with the selective ghrelin-receptor agonist Ipamorelin. CJC-1295 lifts the baseline of pulsatile GH release; Ipamorelin amplifies pulse amplitude without driving cortisol, prolactin or ACTH. Dual-receptor stimulation produces a GH response greater than the sum of either alone.

Read the research →
PerformanceResearch vial
Ipamorelin
5mg vial

Ipamorelin

Ipamorelin is a pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) and a selective agonist of the growth-hormone-secretagogue receptor (GHS-R1a) — the same receptor targeted by ghrelin. It triggers pulsatile GH release without the ACTH, cortisol and prolactin spikes seen with older GHRPs (GHRP-2, GHRP-6, hexarelin).

Read the research →
PerformanceResearch vial
Hexarelin
5mg vial

Hexarelin

Hexarelin is a synthetic hexapeptide analog of GHRP-6 and a potent agonist of the growth-hormone-secretagogue receptor (GHS-R1a). It also binds the non-GHS-R receptor CD36, which underlies a separate cardiac action that does not depend on GH release. Of the older GHRPs it produces the strongest GH pulse.

Read the research →
Publisher
Elegant Slimming · Mokopane, Limpopo, South Africa
Research library · nothing on this site is for sale.
Regulatory
This compound has not been evaluated by the South African Health Products Regulatory Authority (SAHPRA).
For information purposes only — not intended to diagnose, treat, cure or prevent any disease.