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Not evaluated by SAHPRA · Research & educational information only · Nothing on this site is for sale · Not medical advice · Consult a healthcare professional
Not evaluated by SAHPRA. Research & educational information only — nothing is for sale; not intended to diagnose, treat, cure or prevent any disease.
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RecoveryResearch vialrecoveryinflammationgutimmunetripeptide

KPV

alpha-MSH-derived tripeptide for gut and airway inflammation.

Format
Research vial
Strength / pack
10mg vial
Category
Recovery
Cytokine suppressionInhibits NF-kB and MAP-kinase signalling at nanomolar concentrations.
Gut inflammationOral KPV reduced disease severity in DSS- and TNBS-induced colitis models.
Airway calmingSuppresses inflammation in human bronchial epithelial cell work.
TNF-a and IL-6 reductionLowers pro-inflammatory cytokine output in cell and rodent studies.
KPV is a tripeptide — lysine, proline, valine — corresponding to the C-terminal fragment of alpha-melanocyte-stimulating hormone (α-MSH). Unlike α-MSH it acts independently of the melanocortin receptors; its anti-inflammatory effect is mediated by uptake through the PepT1 transporter expressed on intestinal epithelial and immune cells.
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Publisher
Elegant Slimming · Mokopane, Limpopo, South Africa
Research library · nothing on this site is for sale.
Regulatory
This compound has not been evaluated by the South African Health Products Regulatory Authority (SAHPRA).
For information purposes only — not intended to diagnose, treat, cure or prevent any disease.