Skip to content
Not evaluated by SAHPRA · Research & educational information only · Nothing on this site is for sale · Not medical advice · Consult a healthcare professional
Not evaluated by SAHPRA. Research & educational information only — nothing is for sale; not intended to diagnose, treat, cure or prevent any disease.
← Back to catalogue
EnergyResearch vialAMPKmitochondrialinsulin sensitivitymetabolicenergy

MOTS-c

Mitochondrial-derived peptide that activates AMPK to lift glucose disposal and fat oxidation

Format
Research vial
Strength / pack
40mg vial
Category
Energy
AMPK activationSwitches on the cell's master energy sensor via AICAR accumulation
Glucose disposalIncreases skeletal-muscle glucose uptake in clamp studies
Metabolic shiftPushes fuel use toward fat oxidation
Exercise-linkedEndogenous levels rise ~1.5-fold with exercise
MOTS-c is a 16-amino-acid peptide encoded by the mitochondrial 12S rRNA gene — one of a small class of "mitochondrial-derived peptides" the body makes from its own mitochondrial DNA. It activates AMPK, the cell's master energy sensor, by perturbing the folate cycle so AICAR accumulates and switches AMPK on. The downstream effect is increased glucose uptake into skeletal muscle and a shift toward fat oxidation.
Publisher
Elegant Slimming · Mokopane, Limpopo, South Africa
Research library · nothing on this site is for sale.
Regulatory
This compound has not been evaluated by the South African Health Products Regulatory Authority (SAHPRA).
For information purposes only — not intended to diagnose, treat, cure or prevent any disease.