Not evaluated by SAHPRA. Research & educational information only — nothing is for sale; not intended to diagnose, treat, cure or prevent any disease.
Hormone BalanceResearch viallibidohsddfda-approvedmelanocortinresearch
PT-141 (Bremelanotide)
Central melanocortin agonist for sexual desire
- Format
- Research vial
- Strength / pack
- 10mg vial
- Category
- Hormone Balance
FDA-approved for HSDDApproved in 2019 as Vyleesi for acquired, generalised hypoactive sexual desire disorder in premenopausal women — an outlier on this list with a fully approved indication.
Significant desire-domain improvementRECONNECT Phase 3 trials (n=1,247): FSFI-desire rose 0.30–0.42 points and FSDS distress fell 0.29–0.37 points versus placebo (P<0.001).
Sustained effect over 24 weeksEffects appeared within the first month and held to week 24 of as-needed dosing.
Central mechanism, not vascularUnlike PDE5 inhibitors, acts on brain desire circuits — explored in men with ED unresponsive to PDE5s.
PT-141, generic name bremelanotide, is a synthetic cyclic heptapeptide derived from α-MSH. It is a non-selective melanocortin receptor agonist with primary activity at MC4R in the hypothalamus and limbic system, acting on the central neural circuits of sexual desire rather than on peripheral blood flow. The FDA approved it in 2019 as Vyleesi for acquired, generalised hypoactive sexual desire disorder (HSDD) in premenopausal women — making PT-141 an outlier on this list with a fully approved indication.
More in Hormone Balance
Related research
Hormone BalanceCapsules
60 capsules
DIM+
Diindolylmethane (a metabolite from cruciferous vegetables) — supports healthy estrogen metabolism and hormonal balance.
Read the research →
Hormone BalanceResearch vial
5000iu vial
HCG
Human chorionic gonadotropin — a glycoprotein hormone that mimics LH at the testicular Leydig-cell receptor, driving endogenous testosterone and sperm production. Decades of human clinical use, well outside the typical research-peptide category.
Read the research →
Hormone BalanceResearch vial
75iu vial
HMG
Human menopausal gonadotropin — a urinary preparation carrying roughly 75 IU each of FSH and LH activity per ampoule. Drives follicular development in women and Sertoli-cell-mediated spermatogenesis in men.
Read the research →
Publisher
Elegant Slimming · Mokopane, Limpopo, South Africa
Research library · nothing on this site is for sale.
Regulatory
This compound has not been evaluated by the South African Health Products Regulatory Authority (SAHPRA).
For information purposes only — not intended to diagnose, treat, cure or prevent any disease.