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Not evaluated by SAHPRA · For information & research use only · Not intended to diagnose, treat, cure or prevent any disease · Consult a healthcare professional
This product has not been evaluated by SAHPRA. For information purposes only — not intended to diagnose, treat, cure or prevent any disease.
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Hormone BalanceResearch viallibidohsddfda-approvedmelanocortinresearch

PT-141 (Bremelanotide)

Central melanocortin agonist for sexual desire

R 455
10mg vial
1
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FDA-approved for HSDDApproved in 2019 as Vyleesi for acquired, generalised hypoactive sexual desire disorder in premenopausal women — an outlier on this list with a fully approved indication.
Significant desire-domain improvementRECONNECT Phase 3 trials (n=1,247): FSFI-desire rose 0.30–0.42 points and FSDS distress fell 0.29–0.37 points versus placebo (P<0.001).
Sustained effect over 24 weeksEffects appeared within the first month and held to week 24 of as-needed dosing.
Central mechanism, not vascularUnlike PDE5 inhibitors, acts on brain desire circuits — explored in men with ED unresponsive to PDE5s.
PT-141, generic name bremelanotide, is a synthetic cyclic heptapeptide derived from α-MSH. It is a non-selective melanocortin receptor agonist with primary activity at MC4R in the hypothalamus and limbic system, acting on the central neural circuits of sexual desire rather than on peripheral blood flow. The FDA approved it in 2019 as Vyleesi for acquired, generalised hypoactive sexual desire disorder (HSDD) in premenopausal women — making PT-141 an outlier on this list with a fully approved indication.
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Distributor
Elegant Slimming · Mokopane, Limpopo, South Africa
WhatsApp 076 547 8764 · Mon–Sat 9–5
Regulatory
This product has not been evaluated by the South African Health Products Regulatory Authority (SAHPRA).
For information purposes only — not intended to diagnose, treat, cure or prevent any disease.